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Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis
Insig-1 and Insig-2 are closely related proteins of the endoplasmic reticulum (ER) that mediate feedback control of cholesterol synthesis by sterol-dependent binding to the following two membrane proteins: the escort protein Scap, thus preventing proteolytic processing of sterol regulatory element-b...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1435366/ https://ncbi.nlm.nih.gov/pubmed/16606821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601923103 |
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