Ischemia reperfusion dysfunction changes model-estimated kinetics of myofilament interaction due to inotropic drugs in isolated hearts

BACKGROUND: The phase-space relationship between simultaneously measured myoplasmic [Ca(2+)] and isovolumetric left ventricular pressure (LVP) in guinea pig intact hearts is altered by ischemic and inotropic interventions. Our objective was to mathematically model this phase-space relationship betwe...

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Detalhes bibliográficos
Main Authors: Rhodes, Samhita S, Camara, Amadou KS, Ropella, Kristina M, Audi, Said H, Riess, Matthias L, Pagel, Paul S, Stowe, David F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1431537/
https://ncbi.nlm.nih.gov/pubmed/16512898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-5-16
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