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Regulation and Role of Raf-1/B-Raf Heterodimerization

The Ras-Raf-MEK-extracellular signal-regulated kinase (ERK) pathway participates in the control of many fundamental cellular processes including proliferation, survival, and differentiation. The pathway is deregulated in up to 30% of human cancers, often due to mutations in Ras and the B-Raf isoform...

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Detalhes bibliográficos
Main Authors: Rushworth, Linda K., Hindley, Alison D., O'Neill, Eric, Kolch, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430271/
https://ncbi.nlm.nih.gov/pubmed/16508002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2262-2272.2006
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