Chargement en cours...

Heterogeneous nuclear ribonucleoprotein H Blocks MST2-Dependent Apoptosis in Cancer Cells via Regulation of A-Raf transcription

A-Raf belongs to the family of oncogenic Raf kinases that are involved in mitogenic signalling by activating the MEK-ERK pathway. Low kinase activity of A-Raf towards MEK suggested that A-Raf might have alternative functions. We show that A-Raf prevents cancer cell apoptosis contingent on the expres...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rauch, Jens, O'Neill, Eric, Mack, Brigitte, Matthias, Christoph, Munz, Markus, Kolch, Walter, Gires, Olivier
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880479/
https://ncbi.nlm.nih.gov/pubmed/20145135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2740
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!