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Heterogeneous nuclear ribonucleoprotein H Blocks MST2-Dependent Apoptosis in Cancer Cells via Regulation of A-Raf transcription
A-Raf belongs to the family of oncogenic Raf kinases that are involved in mitogenic signalling by activating the MEK-ERK pathway. Low kinase activity of A-Raf towards MEK suggested that A-Raf might have alternative functions. We show that A-Raf prevents cancer cell apoptosis contingent on the expres...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880479/ https://ncbi.nlm.nih.gov/pubmed/20145135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2740 |
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