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The Proteasome Is Required for Rapid Initiation of Death Receptor-Induced Apoptosis
Due to their tremendous apoptosis-inducing potential, proteasomal inhibitors (PIs) have recently entered clinical trials. Here we show, however, that various PIs rescued proliferating tumor cells from death receptor-induced apoptosis. This protection correlated with the stabilization of X-linked IAP...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1430261/ https://ncbi.nlm.nih.gov/pubmed/16479014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1967-1978.2006 |
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