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Protein Phosphatase 2A Antagonizes ATM and ATR in a Cdk2- and Cdc7-Independent DNA Damage Checkpoint

We previously used a soluble cell-free system derived from Xenopus eggs to investigate the role of protein phosphatase 2A (PP2A) in chromosomal DNA replication. We found that immunodepletion of PP2A or inhibition of PP2A by okadaic acid (OA) inhibits initiation of DNA replication by preventing loadi...

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Bibliografische gegevens
Hoofdauteurs: Petersen, Paris, Chou, Danny M., You, Zhongsheng, Hunter, Tony, Walter, Johannes C., Walter, Gernot
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430240/
https://ncbi.nlm.nih.gov/pubmed/16479016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1997-2011.2006
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