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Protein Phosphatase 5 Is Required for ATR-Mediated Checkpoint Activation

In response to DNA damage or replication stress, the protein kinase ATR is activated and subsequently transduces genotoxic signals to cell cycle control and DNA repair machinery through phosphorylation of a number of downstream substrates. Very little is known about the molecular mechanism by which...

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Detalhes bibliográficos
Main Authors: Zhang, Ji, Bao, Shideng, Furumai, Ryohei, Kucera, Katerina S., Ali, Ambereen, Dean, Nicolas M., Wang, Xiao-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280286/
https://ncbi.nlm.nih.gov/pubmed/16260606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.9910-9919.2005
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