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Screen for Inhibitors of the Coupled Transglycosylase-Transpeptidase of Peptidoglycan Biosynthesis in Escherichia coli

Class A high-molecular-weight penicillin-binding protein 1a (PBP1a) and PBP1b of Escherichia coli have both transglycosylase (TG) and transpeptidase (TP) activity. These enzymes are difficult to assay, since their substrates are difficult to prepare. We show the activity of PBP1a or PBP1b can be mea...

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Bibliografische gegevens
Hoofdauteurs: Ramachandran, Vasanthi, Chandrakala, B., Kumar, Vidya P., Usha, Veeraraghavan, Solapure, Suresh M., de Sousa, Sunita M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426922/
https://ncbi.nlm.nih.gov/pubmed/16569861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1425-1432.2006
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