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The secreted Salmonella dublin phosphoinositide phosphatase, SopB, localizes to PtdIns(3)P-containing endosomes and perturbs normal endosome to lysosome trafficking

Invasion and survival in mammalian cells by Salmonella enterica is mediated by bacterial proteins that are delivered to the host cell cytoplasm by type III secretion systems. One of these proteins, SopB/SigD, is a phosphoinositide phosphatase that can hydrolyse a number of substrates in vitro includ...

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Detalhes bibliográficos
Main Authors: Dukes, Joseph D., Lee, Huailo, Hagen, Rachel, Reaves, Barbara J., Layton, Abigail N., Galyov, Edouard E., Whitley, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422764/
https://ncbi.nlm.nih.gov/pubmed/16396630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051451
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