The secreted Salmonella dublin phosphoinositide phosphatase, SopB, localizes to PtdIns(3)P-containing endosomes and perturbs normal endosome to lysosome trafficking

Invasion and survival in mammalian cells by Salmonella enterica is mediated by bacterial proteins that are delivered to the host cell cytoplasm by type III secretion systems. One of these proteins, SopB/SigD, is a phosphoinositide phosphatase that can hydrolyse a number of substrates in vitro includ...

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Autors principals: Dukes, Joseph D., Lee, Huailo, Hagen, Rachel, Reaves, Barbara J., Layton, Abigail N., Galyov, Edouard E., Whitley, Paul
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422764/
https://ncbi.nlm.nih.gov/pubmed/16396630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051451
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