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Structural evidence for induced fit and a mechanism for sugar/H(+) symport in LacY
Cation-coupled active transport is an essential cellular process found ubiquitously in all living organisms. Here, we present two novel ligand-free X-ray structures of the lactose permease (LacY) of Escherichia coli determined at acidic and neutral pH, and propose a model for the mechanism of coupli...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1422171/ https://ncbi.nlm.nih.gov/pubmed/16525509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601028 |
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