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Properties of a LacY efflux mutant

Crystal structures of lactose permease from Escherichia coli (LacY) exhibit two six-helix bundles with two-fold pseudo-symmetry separated by a large hydrophilic cavity. The cavity is open only on the cytoplasmic side and contains the side chains important for both sugar and H(+) binding at the apex...

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Detalhes bibliográficos
Main Authors: Guan, Lan, Kaback, H. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754601/
https://ncbi.nlm.nih.gov/pubmed/19719233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9014067
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