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Redundancy of DNA helicases in p53-mediated apoptosis

A subset of DNA helicases, the RecQ family, has been found to be associated with the p53-mediated apoptotic pathway and is involved in maintaining genomic integrity. This family contains the BLM and WRN helicases, in which germline mutations are responsible for Bloom and Werner syndromes, respective...

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Bibliografiske detaljer
Main Authors: Spillare, EA, Wang, XW, von Kobbe, C, Bohr, VA, Hickson, ID, Harris, CC
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1420682/
https://ncbi.nlm.nih.gov/pubmed/16288211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209242
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