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p53-Mediated apoptosis is attenuated in Werner syndrome cells

The WRN DNA helicase is a member of the DExH-containing DNA helicase superfamily that includes XPB, XPD, and BLM. Mutations in WRN are found in patients with the premature aging and cancer susceptibility syndrome known as Werner syndrome (WS). p53 binds to the WRN protein in vivo and in vitro throug...

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Bibliografske podrobnosti
Main Authors: Spillare, Elisa A., Robles, Ana I., Wang, Xin Wei, Shen, Jiang-Cheng, Yu, Chang-Eu, Schellenberg, Gerard D., Harris, Curtis C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC316776/
https://ncbi.nlm.nih.gov/pubmed/10364153
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