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Clinical Outcomes and Correlates of TP53 Mutations and Cancer

The initial observation that p53 accumulation might serve as a surrogate biomarker for TP53 mutation has been the cornerstone for vast translational efforts aimed at validating its clinical use for the diagnosis, prognosis, and treatment of cancer. Early on, it was realized that accurate evaluation...

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Detalhes bibliográficos
Main Authors: Robles, Ana I., Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829964/
https://ncbi.nlm.nih.gov/pubmed/20300207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001016
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