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Clinical Outcomes and Correlates of TP53 Mutations and Cancer

The initial observation that p53 accumulation might serve as a surrogate biomarker for TP53 mutation has been the cornerstone for vast translational efforts aimed at validating its clinical use for the diagnosis, prognosis, and treatment of cancer. Early on, it was realized that accurate evaluation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Robles, Ana I., Harris, Curtis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829964/
https://ncbi.nlm.nih.gov/pubmed/20300207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001016
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