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Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling
Individuals with Down syndrome (DS) are predisposed to develop acute megakaryoblastic leukemia (AMKL), characterized by expression of truncated GATA1 transcription factor protein (GATA1s) due to somatic mutation. The treatment outcome for DS-AMKL is more favorable than for AMKL in non-DS patients. T...
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| Autors principals: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413912/ https://ncbi.nlm.nih.gov/pubmed/16492768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511150103 |
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