Cargando...

Peptides selected for binding to clotted plasma accumulate in tumor stroma and wounds

Screening of a phage library for peptides that bind to clotted plasma in the presence of liquid plasma yielded two cyclic decapeptides, CGLIIQKNEC (CLT1) and CNAGESSKNC (CLT2). When injected intravenously into mice bearing various types of tumors, fluorescein-conjugated CLT peptides accumulated in a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pilch, Jan, Brown, Darren M., Komatsu, Masanobu, Järvinen, Tero A. H., Yang, Meng, Peters, David, Hoffman, Robert M., Ruoslahti, Erkki
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413849/
https://ncbi.nlm.nih.gov/pubmed/16476999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511219103
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!