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Activated Src abrogates the Myc requirement for the G(0)/G(1) transition but not for the G(1)/S transition
The transcription factor Myc plays a central role in the control of cellular proliferation. Myc expression is induced by growth factors in a pathway mediated by cellular Src (c-Src), but it is not clear whether Myc induction or activity is required for malignant transformation by activated Src. We i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413844/ https://ncbi.nlm.nih.gov/pubmed/16477001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511186103 |
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