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Epigenetics of human T cells during the G(0)→G(1) transition

We investigated functional epigenetic changes that occur in primary human T lymphocytes during entry into the cell cycle and mapped these at the single-nucleosome level by ChIP-chip on tiling arrays for chromosomes 1 and 6. We show that nucleosome loss and flanking active histone marks define active...

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Detalhes bibliográficos
Main Authors: Smith, Alexander E., Chronis, Constantinos, Christodoulakis, Manolis, Orr, Stephen J., Lea, Nicholas C., Twine, Natalie A., Bhinge, Akshay, Mufti, Ghulam J., Thomas, N. Shaun B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720178/
https://ncbi.nlm.nih.gov/pubmed/19546172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.085530.108
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