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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

Increased production of mitochondrial reactive oxygen species (ROS) by hyperglycemia is recognized as a major cause of the clinical complications associated with diabetes and obesity [Brownlee, M. (2001) Nature 414, 813–820]. We observed that dynamic changes in mitochondrial morphology are associate...

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Autors principals: Yu, Tianzheng, Robotham, James L., Yoon, Yisang
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413838/
https://ncbi.nlm.nih.gov/pubmed/16477035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511154103
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