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Oxygen Sensitivity of Mitochondrial Reactive Oxygen Species Generation Depends on Metabolic Conditions

The mitochondrial generation of reactive oxygen species (ROS) plays a central role in many cell signaling pathways, but debate still surrounds its regulation by factors, such as substrate availability, [O(2)] and metabolic state. Previously, we showed that in isolated mitochondria respiring on succi...

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Detalhes bibliográficos
Main Authors: Hoffman, David L., Brookes, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713566/
https://ncbi.nlm.nih.gov/pubmed/19366681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809512200
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