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Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

Mitochondria-derived reactive oxygen species (mROS) are required for the survival, proliferation, and metastasis of cancer cells. The mechanism by which mitochondrial metabolism regulates mROS levels to support cancer cells is not fully understood. To address this, we conducted a metabolism-focused...

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Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Kong, Hyewon, Reczek, Colleen R., McElroy, Gregory S., Steinert, Elizabeth M., Wang, Tim, Sabatini, David M., Chandel, Navdeep S.
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673681/
https://ncbi.nlm.nih.gov/pubmed/33148642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb7272
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