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Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

Mitochondria-derived reactive oxygen species (mROS) are required for the survival, proliferation, and metastasis of cancer cells. The mechanism by which mitochondrial metabolism regulates mROS levels to support cancer cells is not fully understood. To address this, we conducted a metabolism-focused...

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書目詳細資料
發表在:Sci Adv
Main Authors: Kong, Hyewon, Reczek, Colleen R., McElroy, Gregory S., Steinert, Elizabeth M., Wang, Tim, Sabatini, David M., Chandel, Navdeep S.
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673681/
https://ncbi.nlm.nih.gov/pubmed/33148642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb7272
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