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Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles
The multifunctional DNA repair enzymes apurinic/apyrimidinic (AP) endonucleases cleave DNA at AP sites and 3′-blocking moieties generated by DNA glycosylases in the base excision repair pathway. Alternatively, in the nucleotide incision repair (NIR) pathway, the same AP endonucleases incise DNA 5′ o...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413785/ https://ncbi.nlm.nih.gov/pubmed/16473948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508582103 |
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