WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

SLC12A cation/Cl(−) cotransporters are mutated in human disease, are targets of diuretics, and are collectively involved in the regulation of cell volume, neuronal excitability, and blood pressure. This gene family has two major branches with different physiological functions and inverse regulation:...

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Detalhes bibliográficos
Main Authors: de los Heros, Paola, Kahle, Kristopher T., Rinehart, Jesse, Bobadilla, Norma A., Vázquez, Norma, San Cristobal, Pedro, Mount, David B., Lifton, Richard P., Hebert, Steven C., Gamba, Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413675/
https://ncbi.nlm.nih.gov/pubmed/16446421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510947103
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