Targeting the Variable Surface of African Trypanosomes with Variant Surface Glycoprotein-Specific, Serum-Stable RNA Aptamers

African trypanosomes cause sleeping sickness in humans and Nagana in cattle. The parasites multiply in the blood and escape the immune response of the infected host by antigenic variation. Antigenic variation is characterized by a periodic change of the parasite protein surface, which consists of a...

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Vydáno v:	Eukaryot Cell
Hlavní autoři:	Lorger, Mihaela, Engstler, Markus, Homann, Matthias, Göringer, H. Ulrich
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12582125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/EC.2.1.84-94.2003
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