Targeting the Variable Surface of African Trypanosomes with Variant Surface Glycoprotein-Specific, Serum-Stable RNA Aptamers

African trypanosomes cause sleeping sickness in humans and Nagana in cattle. The parasites multiply in the blood and escape the immune response of the infected host by antigenic variation. Antigenic variation is characterized by a periodic change of the parasite protein surface, which consists of a...

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Bibliografische Detailangaben

Veröffentlicht in:	Eukaryot Cell
Hauptverfasser:	Lorger, Mihaela, Engstler, Markus, Homann, Matthias, Göringer, H. Ulrich
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12582125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/EC.2.1.84-94.2003
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