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Immunodominant surface epitopes power immune evasion in the African trypanosome

Summary: The African trypanosome survives the immune response of its mammalian host by antigenic variation of its major surface antigen (the variant surface glycoprotein or VSG). Here we describe the antibody repertoires elicited by different VSGs. We show that the repertoires are highly restricted...

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Hlavní autoři: Anastasia Gkeka, Francisco Aresta-Branco, Gianna Triller, Evi P. Vlachou, Monique van Straaten, Mirjana Lilic, Paul Dominic B. Olinares, Kathryn Perez, Brian T. Chait, Renata Blatnik, Thomas Ruppert, Joseph P. Verdi, C. Erec Stebbins, F. Nina Papavasiliou
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2023-03-01
Edice:Cell Reports
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211124723002735
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