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Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber

The initial recognition and binding of adenovirus vector to the host cell surface is mediated by interaction between the adenovirus fiber knob protein and its receptor, the coxsackievirus and adenovirus receptor (CAR). This natural tropism of adenovirus vector needs to be ablated in order to achieve...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Nakamura, Takafumi, Sato, Kenzo, Hamada, Hirofumi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2003
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12551989/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2512-2521.2003
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