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Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber

The initial recognition and binding of adenovirus vector to the host cell surface is mediated by interaction between the adenovirus fiber knob protein and its receptor, the coxsackievirus and adenovirus receptor (CAR). This natural tropism of adenovirus vector needs to be ablated in order to achieve...

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Bibliografiske detaljer
Main Authors: Nakamura, Takafumi, Sato, Kenzo, Hamada, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141073/
https://ncbi.nlm.nih.gov/pubmed/12551989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2512-2521.2003
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