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Reduction of Natural Adenovirus Tropism to the Liver by both Ablation of Fiber-Coxsackievirus and Adenovirus Receptor Interaction and Use of Replaceable Short Fiber

The initial recognition and binding of adenovirus vector to the host cell surface is mediated by interaction between the adenovirus fiber knob protein and its receptor, the coxsackievirus and adenovirus receptor (CAR). This natural tropism of adenovirus vector needs to be ablated in order to achieve...

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Vydáno v:J Virol
Hlavní autoři: Nakamura, Takafumi, Sato, Kenzo, Hamada, Hirofumi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141073/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12551989/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2512-2521.2003
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