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Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 35

Oncolytic adenoviruses (OAds) are among the most promising oncolytic viruses. Almost all oncolytic adenoviruses are composed of human adenovirus serotype 5 (Ad5) (OAd5). However, expression of the primary infection receptor for Ad5, coxsackievirus-adenovirus receptor (CAR), often declines on maligna...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Ryosuke Ono, Kosuke Takayama, Fuminori Sakurai, Hiroyuki Mizuguchi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021-03-01
Schriftenreihe:Molecular Therapy: Oncolytics
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2372770521000164
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