Rational design of low-molecular weight heparins with improved in vivo activity

Heparin and low-molecular weight heparins (LMWHs), complex, sulfated polysaccharides isolated from endogenous sources, are potent modulators of hemostasis. Heparin and LMWHs interact with multiple components of the coagulation cascade to inhibit the clotting process. Pharmaceutical preparations of t...

Description complète

Détails bibliographiques

Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Sundaram, Mallik, Qi, Yiwei, Shriver, Zachary, Liu, Dongfang, Zhao, Ganlin, Venkataraman, Ganesh, Langer, Robert, Sasisekharan, Ram
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141051/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252643299
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!