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Mass spectrometric evidence for the enzymatic mechanism of the depolymerization of heparin-like glycosaminoglycans by heparinase II

Heparin-like glycosaminoglycans, acidic complex polysaccharides present on cell surfaces and in the extracellular matrix, regulate important physiological processes such as anticoagulation and angiogenesis. Heparin-like glycosaminoglycan degrading enzymes or heparinases are powerful tools that have...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Rhomberg, Andrew J., Shriver, Zachary, Biemann, Klaus, Sasisekharan, Ram
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12232
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