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Rational design of low-molecular weight heparins with improved in vivo activity
Heparin and low-molecular weight heparins (LMWHs), complex, sulfated polysaccharides isolated from endogenous sources, are potent modulators of hemostasis. Heparin and LMWHs interact with multiple components of the coagulation cascade to inhibit the clotting process. Pharmaceutical preparations of t...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141051/ https://ncbi.nlm.nih.gov/pubmed/12525684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252643299 |
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