Rational design of low-molecular weight heparins with improved in vivo activity

Heparin and low-molecular weight heparins (LMWHs), complex, sulfated polysaccharides isolated from endogenous sources, are potent modulators of hemostasis. Heparin and LMWHs interact with multiple components of the coagulation cascade to inhibit the clotting process. Pharmaceutical preparations of t...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Sundaram, Mallik, Qi, Yiwei, Shriver, Zachary, Liu, Dongfang, Zhao, Ganlin, Venkataraman, Ganesh, Langer, Robert, Sasisekharan, Ram
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141051/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12525684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252643299
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!