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Structure–activity relationships of the human prothrombin kringle-2 peptide derivative NSA9: anti-proliferative activity and cellular internalization

The human prothrombin kringle-2 protein inhibits angiogenesis and LLC (Lewis lung carcinoma) growth and metastasis in mice. Additionally, the NSA9 peptide (NSAVQLVEN) derived from human prothrombin kringle-2 has been reported to inhibit the proliferation of BCE (bovine capillary endothelial) cells a...

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Detalles Bibliográficos
Main Authors: Hwang, Hyun Sook, Kim, Dong Won, Kim, Soung Soo
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409683/
https://ncbi.nlm.nih.gov/pubmed/16390327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051300
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