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Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila
A subset of patients suffering from familial amyotrophic lateral sclerosis (FALS) exhibit point mutations in the gene encoding Cu-Zn superoxide dismutase [superoxide:superoxide oxidoreductase, EC 1.15.1.1 (SOD)]. The human wild-type and five FALS Sod mutant transgenes were introduced into the fruit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140958/ https://ncbi.nlm.nih.gov/pubmed/12502789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136976100 |
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