Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5

Double-stranded RNAs ≈21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to reduce the expression of specific genes. To use them as reagents to protect cells against viral infection, effective methods for introducing siRNAs into primary cells are required. Here,...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Qin, Xiao-Feng, An, Dong Sung, Chen, Irvin S. Y., Baltimore, David
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12518064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232688199
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