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MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

MicroRNAs (miRNAs) are endogenously encoded small noncoding RNAs, derived by processing of short RNA hairpins, that can inhibit the translation of mRNAs bearing partially complementary target sequences. In contrast, small interfering RNAs (siRNAs), which are derived by processing of long double-stra...

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Autors principals: Zeng, Yan, Yi, Rui, Cullen, Bryan R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC187842/
https://ncbi.nlm.nih.gov/pubmed/12902540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1630797100
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