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Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5

Double-stranded RNAs ≈21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to reduce the expression of specific genes. To use them as reagents to protect cells against viral infection, effective methods for introducing siRNAs into primary cells are required. Here,...

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Detalhes bibliográficos
Main Authors: Qin, Xiao-Feng, An, Dong Sung, Chen, Irvin S. Y., Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140921/
https://ncbi.nlm.nih.gov/pubmed/12518064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232688199
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