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Insufficiently dehydrated hydrogen bonds as determinants of protein interactions

The prediction of binding sites and the understanding of interfaces associated with protein complexation remains an open problem in molecular biophysics. This work shows that a crucial factor in predicting and rationalizing protein–protein interfaces can be inferred by assessing the extent of intram...

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Detalhes bibliográficos
Main Authors: Fernández, Ariel, Scheraga, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140898/
https://ncbi.nlm.nih.gov/pubmed/12518060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0136888100
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