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Revisiting the Carboxylic Acid Dimers in Aqueous Solution: Interplay of Hydrogen Bonding, Hydrophobic Interactions, and Entropy

Carboxylic acid dimers are useful model systems for understanding the interplay of hydrogen bonding, hydrophobic effects, and entropy in self-association and assembly. Through extensive sampling with a classical force field and careful free energy analysis, it is demonstrated that both hydrogen bond...

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Detalhes bibliográficos
Main Authors: Chen, Jianhan, Brooks, Charles L., Scheraga, Harold A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561919/
https://ncbi.nlm.nih.gov/pubmed/17880128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp074355h
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