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Role of HNF4α in the superinduction of the IL-1β-activated iNOS gene by oxidative stress
IL-1β (interleukin-1β) treatment of hepatocytes results in an NF-κB (nuclear factor-κB)-mediated activation of the iNOS (induced nitric oxide synthase) gene, and this increase in gene expression is further augmented by oxidative stress. Oxidative stress alone has no influence on the iNOS promoter, t...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1408685/ https://ncbi.nlm.nih.gov/pubmed/16479620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060005 |
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