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Identification of hamster inducible nitric oxide synthase (iNOS) promoter sequences that influence basal and inducible iNOS expression

IFN-γ/LPS-activated hamster (Mesocricetus auratus) macrophages express significantly less iNOS (NOS2) than activated mouse macrophages, which contributes to the hamster's susceptibility to intracellular pathogens. We determined a mechanism responsible for differences in iNOS promoter activity i...

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Détails bibliographiques
Auteurs principaux: Saldarriaga, Omar A., Travi, Bruno L., Choudhury, Goutam Ghosh, Melby, Peter C.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382312/
https://ncbi.nlm.nih.gov/pubmed/22517919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1010568
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