Inorganic Polyphosphate Suppresses Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase (iNOS) Expression in Macrophages

In response to infection, macrophages produce a series of inflammatory mediators, including nitric oxide (NO), to eliminate pathogens. The production of these molecules is tightly regulated via various mechanisms, as excessive responses are often detrimental to host tissues. Here, we report that ino...

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Главные авторы: Harada, Kana, Shiba, Toshikazu, Doi, Kazuya, Morita, Koji, Kubo, Takayasu, Makihara, Yusuke, Piattelli, Adriano, Akagawa, Yasumasa
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767636/
https://ncbi.nlm.nih.gov/pubmed/24040305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074650
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