Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression

BACKGROUND AND PURPOSE: Pharmacological inhibition of beta-amyloid (Aβ) induced reactive gliosis may represent a novel rationale to develop drugs able to blunt neuronal damage and slow the course of Alzheimer's disease (AD). Cannabidiol (CBD), the main non-psychotropic natural cannabinoid, exer...

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Bibliografske podrobnosti
Main Authors: Esposito, G, Scuderi, C, Savani, C, Steardo, L, De Filippis, D, Cottone, P, Iuvone, T, Cuomo, V
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189818/
https://ncbi.nlm.nih.gov/pubmed/17592514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707337
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