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Scrapie-like prion protein accumulates in aggresomes of cyclosporin A-treated cells

Prion diseases are infectious, sporadic and inherited fatal neurodegenerations that are propagated by an abnormal refolding of the cellular prion protein PrP(C). Which chaperones assist the normal folding of PrP(C) is unknown. The linkage of familial Gerstmann– Sträussler–Scheinker (GSS) syndrome wi...

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Publicat a:EMBO J
Autors principals: Cohen, Ehud, Taraboulos, Albert
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554642/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg045
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