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Novel p27(kip1) C-Terminal Scatter Domain Mediates Rac-Dependent Cell Migration Independent of Cell Cycle Arrest Functions

Hepatocyte growth factor (HGF) signaling via its receptor, the proto-oncogene Met, alters cell proliferation and motility and has been associated with tumor metastasis. HGF treatment of HepG2 human hepatocellular carcinoma cells induces cell migration concomitant with increased levels of the p27(kip...

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Autors principals: McAllister, Sandra S., Becker-Hapak, Michelle, Pintucci, Giuseppe, Pagano, Michele, Dowdy, Steven F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC140659/
https://ncbi.nlm.nih.gov/pubmed/12482975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.1.216-228.2003
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